Case of the Month: September 2025
Case history
- 40-year-old patient presented with right-sided sensory disturbance.
- Initial MRI showed a T2-hyperintense lesion in the left precentral gyrus with a rim of diffusion restriction and subtle enhancement.
Click to reveal diagnosis
- Despite steroid therapy, an MRI one month later showed significant enlargement of the lesion, although enhancement had resolved.
- After two months, following plasma exchange, the lesion decreased in size although punctate enhancement developed.
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The characteristic concentric rings of alternating demyelination and preserved myelin are pathognomonic of Baló's concentric sclerosis.